Dr. Norris has broad expertise in the integrative physiology of diabetes. His laboratory studies the early pathogenesis of CFRD in ferret and pig models, with a focus on the extent to which redox stress, lipid abnormalities, and metabolic disease contribute to altered islet function in CFRD. Dr. Norris brings substantial expertise in the study of CFRD pathogenesis to the Center. He is PI on an R01 and an R24 (RC2 renewal pending) that are solely focused on CFRD research, and is co-I on the CFRD clinical trial at UI.