Dr. Parekh’s laboratory focuses on the biology of endogenous airway epithelial stem cells in the development of obliterative bronchiolitis (OB) following lung transplantation. His R01-funded research investigates the mechanisms by which stem cell niches in the lung are destroyed in the transplanted lung (human and ferret), with the long-term goal of developing autologous stem cell-based therapies for the CF lung transplant. His research program has strong synergies with Dr. Engelhardt’s research on lung stem cells.